Provitalize is a dietary supplement that is generally considered safe to take alongside acetaminophen, a commonly used pain reliever. There is no known significant interaction between Provitalize and acetaminophen. This means that it is unlikely for the two substances to have any adverse effects or interfere with each other's effectiveness when taken together. However, as with any supplement or medication, it is always a good idea to consult with a healthcare professional before combining Provitalize with acetaminophen or any other medications to ensure it is safe for your specific situation.