Phytoestrogens, such as isoflavones, have the ability to bind to estrogen receptors in the body. However, they have a limited half-life, which means that they are metabolized and eliminated from the body relatively quickly. For example, isoflavones have a half-life range of around 12-30 hours.
As a result, the benefits of CalmAgain, which contains phytoestrogens, may only last for around 1-2 days. After this time, another dose is needed to maintain the effects. This is because the phytoestrogens are no longer present in sufficient amounts to continue binding to estrogen receptors.
On the other hand, Provitalize works differently. It contains probiotics that are able to colonize and establish themselves in the digestive system. These probiotics can remain in the system for a longer period of time compared to phytoestrogens.
Therefore, the effects of Provitalize can last longer than CalmAgain. The probiotics in Provitalize continue to provide their benefits as long as they remain in the system, which can be for an extended period of time.