While CalmAgain doesn't directly restore estrogen levels post-hysterectomy, it can significantly reduce associated symptoms. The formula's natural ingredients, particularly Menofelis™ Siberian Rhubarb, work by attaching to estrogen receptors to help balance hormones and reduce common post-hysterectomy challenges like anxiety, mood swings, and hot flashes. Many women who have undergone hysterectomies report feeling more balanced and experiencing fewer symptoms when taking CalmAgain.